The PE-Cyanine5 Anti-Rat CD45 Antibody (OX-1) is a powerful tool for researchers studying immune cells in rats. Specifically designed to target CD45, a common marker for leukocytes, this antibody is essential for flow cytometry and immunofluorescence experiments. The high specificity and sensitivity of the PE-Cyanine5 Anti-Rat CD45 Antibody (OX-1) ensure reliable and accurate detection of CD45-positive cells in various rat tissues and samples.
With its exceptional performance and consistent results, this antibody is a valuable asset for studies focusing on immune cell profiling, inflammation, and immune response modulation in rat models. Researchers can rely on the PE-Cyanine5 Anti-Rat CD45 Antibody (OX-1) to enhance their understanding of immune cell populations and their functions, paving the way for advancements in immunology and disease research.
Product Title:
PE/Cyanine5 Anti-Rat CD45 Antibody [OX-1]
SKU:
AGEL2447
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
OX-1
Synonyms:
Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:
Mouse
Reactivity:
Rat
Application:
FCM
Isotype:
Mouse IgG1, κ
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04157
Gene ID:
19265
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.