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PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4] (AGEL2303)

SKU:
AGEL2303
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
29A1.4
Conjugation:
PE/Cyanine5
$275 - $659
Frequently bought together:

Description

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PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4]

The PE-Cyanine5 Anti-Mouse CD335 Antibody (29A1.4) is a vital tool for researchers studying natural killer (NK) cells and their activation mechanisms. This monoclonal antibody, specifically designed for use in flow cytometry applications, targets the CD335 antigen, also known as NKp46, a key marker for NK cell activity and function.NK cells are a crucial component of the innate immune system, responsible for recognizing and eliminating infected or abnormal cells in the body. The CD335 antigen plays a pivotal role in the activation and regulation of NK cells, making it a valuable target for understanding immune responses in various contexts, including viral infections, cancer, and autoimmune diseases.

The PE-Cyanine5 Anti-Mouse CD335 Antibody (29A1.4) is highly specific and reliable for detecting CD335 expression on mouse NK cells, enabling researchers to accurately analyze and characterize these important immune cells. Its use can provide valuable insights into the function and behavior of NK cells, contributing to a deeper understanding of immune responses and potentially leading to the development of novel immunotherapies.

Product Title:PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL2303
Size:25µg, 100µg
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

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