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PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4] (AGEL2301)

SKU:
AGEL2301
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
29A1.4
Conjugation:
PE/Cyanine5
€409 - €939

Description

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PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4]

The PE-Cyanine5 Anti-Mouse CD335 Antibody (29A1.4) is a vital tool for researchers studying immune responses in mice. The antibody specifically targets CD335, also known as NKp46, a cell surface receptor expressed on natural killer (NK) cells and involved in immune cell recognition and activation.Produced for high reactivity and specificity, this antibody is raised in mouse and is validated for use in flow cytometry and immunofluorescence applications. By binding to the CD335 protein, researchers can accurately detect and analyze NK cells in various tissues and experimental conditions, allowing for detailed insights into immune responses in different disease models and treatments.

CD335 is a key player in the innate immune system, mediating NK cell cytotoxicity and cytokine production in response to viral infections, tumors, and other pathological challenges. Understanding how CD335 functions in immune surveillance and response is crucial for developing novel immunotherapies and antiviral strategies. Researchers can leverage the PE-Cyanine5 Anti-Mouse CD335 Antibody (29A1.4) to advance their investigations in immunology, virology, and cancer research, ultimately contributing to the development of new therapeutic approaches.

Product Title:PE/Cyanine5 Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL2301
Size:50 Tests, 100 Tests, 200 Tests
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

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