The PE-Cyanine5 Anti-Human CD48 Antibody (Clone 156-4H9) from Assay Genie is a highly specific monoclonal antibody designed for the detection of the CD48 cell surface protein in human samples. CD48 is known to play a key role in immune responses and is involved in various cellular processes, making it a valuable target for research in immunology and related fields.This antibody, optimized for flow cytometry applications, offers high sensitivity and specificity in detecting CD48 expression on different cell types.
With its superior performance and reliability, researchers can confidently use this antibody to study the functions of CD48 in immune regulation, cell signaling, and disease mechanisms.With its potential applications in immunology, cancer research, and beyond, the PE-Cyanine5 Anti-Human CD48 Antibody (Clone 156-4H9) is a valuable tool for unraveling the complexities of immune responses and advancing our understanding of human health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09326
Gene ID:
962
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.