The PE-Cyanine5 Anti-Human CD4 Antibody (SK3) available at assaygenie.com is a superior tool for researchers studying CD4, a crucial cell surface marker involved in immune responses. This antibody, specifically designed for human samples, is validated for flow cytometry applications with high specificity and sensitivity.CD4, a glycoprotein found on helper T cells, plays a fundamental role in the immune system by facilitating communication between immune cells and coordinating immune responses. The SK3 antibody binds specifically to the CD4 protein, allowing for precise detection and analysis in a variety of cell types.
Its fluorescence properties make it ideal for flow cytometry experiments, providing researchers with a powerful tool for studying immune cell populations and functions.By targeting CD4 with the PE-Cyanine5 Anti-Human CD4 Antibody (SK3), researchers can gain valuable insights into immune system dynamics, autoimmune diseases, infectious disorders, and immunotherapy strategies. This antibody enables accurate identification and quantification of CD4-expressing cells in biological samples, paving the way for advancements in immunology research and the development of innovative therapeutic approaches.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.