The PE-Cyanine5 Anti-Human CD326 Antibody (9C4) offered by Assay Genie is a cutting-edge tool for researchers investigating CD326, a cell adhesion molecule also known as EpCAM. This antibody, excelling in specificity and efficiency, is specifically designed for the detection and analysis of CD326 in human samples. With its high reactivity and validated performance in applications such as flow cytometry and immunofluorescence, the 9C4 antibody opens doors for deepening the understanding of CD326 in diverse cellular contexts.CD326, a crucial player in cell adhesion processes and cell signaling pathways, is known for its involvement in tumorigenesis and cancer progression.
By targeting this molecule, researchers can gain insights into mechanisms underlying tumor development, metastasis, and potential therapeutic interventions. The PE-Cyanine5 Anti-Human CD326 Antibody (9C4) empowers scientists to explore the role of CD326 in cancer biology, stem cell research, and regenerative medicine with precision and confidence. Embrace this innovative tool to advance your studies in oncology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16422
Gene ID:
4072
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.