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PE/Cyanine5 Anti-Human CD22 Antibody [BU59]

SKU:
AGEL2820
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
BU59
Conjugation:
PE/Cyanine5
€209 - €709
Frequently bought together:

Description

PE/Cyanine5 Anti-Human CD22 Antibody [BU59]

The PE-Cyanine5 Anti-Human CD22 Antibody (BU59) offered by Assay Genie is a powerful tool for research involving the CD22 cell surface molecule, which plays a key role in B-cell function and development. This antibody, designed for use with human samples, is ideal for flow cytometry applications, enabling precise identification and analysis of CD22-expressing cells in various research settings.CD22 is a transmembrane glycoprotein expressed specifically on B cells and is involved in B-cell activation and regulation. By targeting CD22, researchers can investigate the function and behavior of B cells in immune responses, autoimmune diseases, and B-cell malignancies.

The PE-Cyanine5 Anti-Human CD22 Antibody (BU59) provides reliable and specific detection of CD22, offering valuable insights into the role of this molecule in health and disease.With its high reactivity and specificity for human CD22, this antibody is a valuable asset for immunology research, particularly in studies related to B-cell biology, antibody responses, and immune system dysregulation. Trust Assay Genie's PE-Cyanine5 Anti-Human CD22 Antibody (BU59) to enhance your research capabilities and advance your understanding of CD22 biology and its implications in various pathological conditions.

Product Name:PE/Cyanine5 Anti-Human CD22 Antibody [BU59]
Product Code:AGEL2820
Clone No:BU59
Synonyms:B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG1, κ
Conjugation:PE/Cyanine5
Form:Liquid
Fluorescent Label:PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Swissprot:P20273
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

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