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PE/Cyanine5 Anti-Human CD20 Antibody [2H7] (AGEL2395)

SKU:
AGEL2395
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, κ
Clone:
2H7
Conjugation:
PE/Cyanine5
€209 - €669

Description

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PE/Cyanine5 Anti-Human CD20 Antibody [2H7]

The PE-Cyanine5 Anti-Human CD20 Antibody (2H7) is a cutting-edge tool designed for precise and reliable detection of the CD20 protein, a cell surface marker primarily found on B cells. This antibody, expertly crafted for research applications, exhibits high affinity and specificity toward human CD20 samples, ensuring accurate and reproducible results in flow cytometry analyses and immunofluorescence studies.Targeting the CD20 protein, which plays a pivotal role in B cell development and function, the PE-Cyanine5 Anti-Human CD20 Antibody (2H7) provides researchers with a powerful tool for investigating B cell-related disorders, such as lymphomas, leukemias, and autoimmune conditions.

By facilitating the identification and characterization of CD20-expressing cells, this antibody enables in-depth exploration of immune responses, disease mechanisms, and potential therapeutic targets in various biological contexts.For scientists and clinicians engaged in immunology, oncology, and related fields, the PE-Cyanine5 Anti-Human CD20 Antibody (2H7) represents a valuable asset in advancing knowledge and discoveries related to B cell biology and associated diseases. With its exceptional specificity and performance, this antibody stands as a key resource for enhancing experimental precision and generating valuable insights into the intricate workings of the immune system.

Product Title:PE/Cyanine5 Anti-Human CD20 Antibody [2H7]
SKU:AGEL2395
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Cyanine5 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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