The PE-Cyanine5 Anti-Human CD1a Antibody (OKT6) offered by AssayGenie is a crucial tool for researching the CD1a protein, a cell surface marker that plays a key role in antigen presentation and immune responses. This antibody, specifically designed for use in flow cytometry applications, is highly specific for human CD1a samples and allows for precise detection and analysis in various cell types.CD1a is a member of the CD1 family of glycoproteins and is primarily found on dendritic cells, mediating the presentation of lipid antigens to T cells. Research involving CD1a is instrumental in understanding immune responses, particularly in the context of infectious diseases, autoimmune disorders, and skin conditions.
By targeting the CD1a protein with the PE-Cyanine5 Anti-Human CD1a Antibody (OKT6), researchers can gain insights into the function and expression of CD1a, advancing studies in immunology, dermatology, and vaccine development.With its high specificity and validated performance in flow cytometry, the PE-Cyanine5 Anti-Human CD1a Antibody (OKT6) is a valuable tool for investigating the role of CD1a in immune responses and disease pathogenesis. This antibody is a must-have for researchers seeking to unravel the complexities of immune regulation and antigen presentation mechanisms in human biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06126
Gene ID:
909
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.