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Key Features

PE/Cyanine5 Anti-Human CD19 Antibody [HI19a] (AGEL3412)

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SKU AGEL3412
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone HI19a
Conjugation PE/Cyanine5
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Description

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PE/Cyanine5 Anti-Human CD19 Antibody [HI19a]

The PE-Cyanine5 Anti-Human CD19 Antibody (HI19A) offered by Assay Genie is a specialized tool for researchers investigating CD19, a cell surface protein widely expressed on B cells. This antibody, optimized for use in flow cytometry applications, exhibits high specificity and sensitivity in detecting CD19 in human samples. It enables precise identification and quantification of CD19-expressing cells, making it an indispensable tool for immunology studies, particularly in the fields of cancer research and hematological disorders.CD19 is a key marker for B cell development and differentiation, playing a vital role in B cell activation and proliferation.

Targeting CD19 has proven to be a successful therapeutic strategy in the treatment of B cell malignancies, such as B cell lymphomas and leukemias. The availability of a reliable antibody like PE-Cyanine5 Anti-Human CD19 (HI19A) facilitates the exploration of CD19 biology and the development of novel immunotherapies targeting CD19-expressing cells.With validated performance and compatibility with various flow cytometry platforms, this antibody from Assay Genie enables researchers to delve deeper into the mechanisms underlying B cell-related diseases and aids in the discovery of potential therapeutic interventions targeting the CD19 protein.

Product Title:PE/Cyanine5 Anti-Human CD19 Antibody [HI19a]
SKU:AGEL3412
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI19a
Synonyms:B-lymphocyte antigen CD19;Cd19;Differentiation antigen CD19;CD19;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P51677
Gene ID:930
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

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