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PE/Cyanine5 Anti-Human CD161 Antibody [HP-3G10] (AGEL2280)

SKU:
AGEL2280
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
HP-3G10
Conjugation:
PE/Cyanine5
€289 - €889
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD161 Antibody [HP-3G10]

The PE-Cyanine5 Anti-Human CD161 Antibody (HP-3G10) offered by Assay Genie is a vital tool for researchers investigating the CD161 cell surface molecule. CD161, also known as NKR-P1A, is a C-type lectin-like receptor expressed on natural killer cells, T cells, and some subsets of B cells. This antibody is specifically designed to target CD161 in human samples, enabling precise detection and analysis in various immunology and cell biology applications.Developed for use in flow cytometry and immunofluorescence studies, the PE-Cyanine5 Anti-Human CD161 Antibody (HP-3G10) provides reliable and reproducible results.

Its high specificity and sensitivity make it an essential reagent for understanding the role of CD161 in immune responses, particularly in the context of infectious diseases, autoimmunity, and cancer.With its proven performance and stringent validation, this antibody is a valuable asset for researchers seeking to unravel the complexities of CD161 biology and its implications in health and disease. Trust Assay Genie to deliver high-quality antibodies that meet the demands of cutting-edge research in immunology and beyond.

Product Title:PE/Cyanine5 Anti-Human CD161 Antibody [HP-3G10]
SKU:AGEL2280
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HP-3G10
Synonyms:CLEC5B; NKRP1A;NKR-P1A;HNKR-P1a;KLRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q12918
Gene ID:3820
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

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