null

PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2356)

SKU:
AGEL2356
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
D7
Conjugation:
PE/Cyanine5.5
€199 - €539
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The PE Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) is a valuable tool for researchers studying mouse Ly6A/E, also known as Sca-1, a cell surface protein associated with stem cell and immune cell identification. This antibody, produced through meticulous processes, demonstrates high specificity and sensitivity in detecting Ly6A/E in mouse samples through flow cytometry and immunofluorescence applications.Ly6A/E, a member of the Ly-6 superfamily, is widely used as a marker for various stem and progenitor cell populations in mice. Its expression pattern and functional relevance in the immune response and stem cell maintenance underscore its significance in developmental biology, regenerative medicine, and immunology research.

Accurate detection and quantification of Ly6A/E through the PE Cyanine5.5-conjugated antibody facilitate precise cell identification and characterization in experimental settings.Researchers exploring stem cell biology, immunology, and tissue regeneration can benefit from the specificity and reliability provided by the PE Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7). By facilitating the visualization and analysis of Ly6A/E-expressing cells, this antibody supports in-depth investigations into cell populations and their roles in physiological and pathological processes in mouse models.

Product Title:PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2356
Size:25µg, 100µg
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Related Products