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PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7] (AGEL2350)

SKU:
AGEL2350
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
D7
Conjugation:
PE/Cyanine5.5
$191 - $467
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]

The PE Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) is a vital tool for researchers studying mouse Ly6A/E (Sca-1), a marker commonly used to identify hematopoietic stem cells and other cell populations in research settings. This antibody, validated for flow cytometry applications, has been specifically designed for high reactivity and specificity in detecting Ly6A/E (Sca-1) in mouse samples.Ly6A/E (Sca-1) is a cell surface marker that plays a crucial role in identifying and characterizing stem cells and progenitor populations in various tissues. Its expression pattern in different cell types makes it an essential tool for researchers studying stem cell biology, regenerative medicine, and various disease models.

By accurately detecting and quantifying Ly6A/E (Sca-1) expression, researchers can gain valuable insights into cell populations and their roles in development, homeostasis, and disease progression.Utilizing the PE Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody (D7) in flow cytometry experiments enables precise identification and isolation of Ly6A/E (Sca-1)-positive cells, facilitating detailed analyses and downstream applications. With its high sensitivity and specificity, this antibody offers researchers a reliable method for investigating the role of Ly6A/E (Sca-1) in various biological processes and disease conditions in mouse models.

Product Title:PE/Cyanine5.5 Anti-Mouse Ly6A/E (Sca-1) Antibody [D7]
SKU:AGEL2350
Size:50 Tests, 100 Tests, 200 Tests
Clone No:D7
Synonyms:Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05533
Gene ID:110454
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

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