The PE-Cyanine5.5 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) is a valuable tool for research involving the LY-6G/LY-6C (GR-1) cell surface marker commonly used for identifying and studying immune cell populations in mice. This antibody is specifically designed for flow cytometry applications, allowing for precise and accurate detection of LY-6G/LY-6C-expressing cells in various tissues and experimental setups.The RB6-8C5 antibody, known for its high sensitivity and specificity, is raised in rabbits and thoroughly validated for its performance in flow cytometry analyses. It binds specifically to the LY-6G/LY-6C (GR-1) antigen, enabling researchers to confidently identify and characterize different immune cell populations, such as neutrophils and inflammatory monocytes, in both healthy and pathological conditions.
Understanding the role of LY-6G/LY-6C (GR-1) in immune responses is essential for investigating inflammation, infection, cancer, and autoimmune diseases in mouse models. By using the PE-Cyanine5.5 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5), researchers can advance their studies in immunology, oncology, and other related fields, uncovering critical insights into immune cell dynamics and function in various disease contexts.
PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.