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PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2169)

SKU:
AGEL2169
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
M1/70
Conjugation:
PE/Cyanine5.5
€109 - €249
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70]

The PE-Cyanine5.5 Anti-Mouse/Human CD11b Antibody (M1/70) offered by Assay Genie is a highly specific antibody designed for the detection of CD11b, a cell surface receptor involved in the adhesion and migration of leukocytes. This antibody, validated for use in flow cytometry applications, is suitable for research focused on immune cell identification and characterization in both mouse and human samples.CD11b, also known as integrin alpha M, plays a crucial role in the regulation of immune responses, particularly in leukocyte adhesion and migration to sites of inflammation or infection. The precise detection of CD11b expression is essential for understanding the dynamics of immune cell populations and their involvement in various physiological and pathological processes.

By utilizing the PE-Cyanine5.5 Anti-Mouse/Human CD11b Antibody (M1/70), researchers can effectively analyze and quantify CD11b expression on different immune cell subsets, aiding in the investigation of immune cell functions, inflammatory responses, and related diseases. This antibody provides a valuable tool for immunology research, offering specific and reliable detection of CD11b to support a wide range of studies in the field.

Product Title:PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL2169
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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