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PE/Cyanine5.5 Anti-Human CD32 Antibody [IV-3] (AGEL3229)

SKU:
AGEL3229
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, k
Clone:
IV-3
Conjugation:
PE/Cyanine5.5
€259 - €889
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human CD32 Antibody [IV-3]

The PE-Cyanine5.5 Anti-Human CD32 Antibody (IV.3) offered by Assay Genie is a valuable tool for researchers investigating the role of CD32, also known as Fc gamma receptor II, in immune responses. This monoclonal antibody specifically targets the CD32 protein, allowing for precise detection and analysis in various experimental settings. With a high level of reactivity towards human CD32, this antibody is ideal for use in flow cytometry and immunofluorescence applications.CD32 is a crucial component of the immune system, playing a significant role in the recognition and clearance of pathogens through interactions with antibodies. Its involvement in modulating immune responses makes it an important target for studies in immunology, infection, and autoimmune diseases.

By understanding the function and expression of CD32, researchers can uncover new insights into immune signaling pathways and potential therapeutic targets for immune-related disorders.The PE-Cyanine5.5 Anti-Human CD32 Antibody (IV.3) from Assay Genie provides researchers with a reliable tool to study the intricate mechanisms of CD32-mediated immune responses. Its specificity and effectiveness in detecting human CD32 make it a valuable asset for investigations into immune regulation, antibody-mediated immunity, and inflammatory processes. Choose this antibody to advance your research and deepen your understanding of the role of CD32 in human health and disease.

Product Title:PE/Cyanine5.5 Anti-Human CD32 Antibody [IV-3]
SKU:AGEL3229
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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