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PE/Cyanine5.5 Anti-Human CD20 Antibody [2H7] (AGEL2397)

SKU:
AGEL2397
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, κ
Clone:
2H7
Conjugation:
PE/Cyanine5.5
€209 - €709
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human CD20 Antibody [2H7]

The PE-Cyanine5.5 Anti-Human CD20 Antibody (2H7) available at www.assaygenie.com is a highly specialized tool for biomedical research focusing on the CD20 protein, a key marker found on B cells. This antibody, optimized for use in flow cytometry applications, is designed to specifically target human CD20, enabling precise identification and analysis of B cells in various samples.CD20 is a crucial protein involved in B cell development and function, making it a valuable target for research in immunology, oncology, and autoimmune diseases. The PE-Cyanine5.5 Anti-Human CD20 Antibody (2H7) provides researchers with a reliable tool for studying B cell populations in both normal and diseased states.

Its high specificity and sensitivity make it an essential resource for exploring the role of CD20 in immune responses, disease pathology, and potential therapeutic interventions.By utilizing this antibody, scientists can gain valuable insights into the dynamics of B cell subsets, monitor changes in CD20 expression under different conditions, and enhance their understanding of B cell-related disorders. The PE-Cyanine5.5 Anti-Human CD20 Antibody (2H7) is a trusted reagent that empowers researchers to advance their studies in immunology and beyond, ultimately contributing to innovative discoveries in biomedical science.

Product Title:PE/Cyanine5.5 Anti-Human CD20 Antibody [2H7]
SKU:AGEL2397
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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