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PE/Cyanine5.5 Anti-Human CD16 Antibody [3G8] (AGEL2770)

SKU:
AGEL2770
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
3G8
Conjugation:
PE/Cyanine5.5
€259 - €889
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human CD16 Antibody [3G8]

The PE-Cyanine5.5 Anti-Human CD16 Antibody (3G8) from AssayGenie is a high-quality monoclonal antibody designed for use in the detection and analysis of CD16, a cell surface receptor involved in immune response modulation. This antibody, optimized for flow cytometry applications, specifically targets the human CD16 protein, allowing for precise identification and characterization of CD16-expressing cells in various biological samples.CD16, also known as FcγRIII, plays a crucial role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis, making it a key player in the immune response against pathogens and tumor cells. By targeting and engaging with CD16, researchers can gain insights into immune cell function, immune cell phenotyping, and antibody efficacy in therapeutic applications.

The PE-Cyanine5.5 Anti-Human CD16 Antibody (3G8) is a valuable tool for studies in immunology, oncology, and infectious diseases. Its high specificity and sensitivity make it an essential component in research aimed at understanding immune cell interactions, identifying therapeutic targets, and developing novel immunotherapies. Trust AssayGenie's expertise and innovation to accelerate your research and uncover new insights into the role of CD16 in immune regulation and disease pathology.

Product Title:PE/Cyanine5.5 Anti-Human CD16 Antibody [3G8]
SKU:AGEL2770
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3G8
Synonyms:FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08637 O75015
Gene ID:941
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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