The PE-Cyanine5.5 Anti-Human CD14 Antibody (M5E2) available at Assay Genie is a high-quality monoclonal antibody specifically designed for research involving the CD14 antigen, a key cell surface marker associated with monocytes and macrophages. This antibody is conjugated with PE-Cyanine5.5, a fluorescent dye suitable for flow cytometry applications, enabling precise and reliable detection of CD14-expressing cells.The M5E2 antibody is meticulously validated for its specificity and sensitivity in identifying CD14-positive cells in human samples, making it an excellent tool for immunophenotyping studies and immune cell identification. The binding capacity of this antibody to the CD14 antigen ensures precise and accurate labeling, allowing researchers to analyze and characterize immune cell populations with confidence and accuracy.
With its application in flow cytometry, the PE-Cyanine5.5 Anti-Human CD14 Antibody (M5E2) offers researchers a valuable tool for investigating immune responses, inflammatory processes, and disease pathologies where CD14 expression is implicated. Its compatibility with various sample types and its reliability in detecting CD14 make it an indispensable asset for studies in immunology, infectious diseases, and inflammatory disorders.In conclusion, the PE-Cyanine5.5 Anti-Human CD14 Antibody (M5E2) from Assay Genie is a premium research reagent that provides researchers with the precision and accuracy needed to study CD14-expressing cells in diverse biological contexts. Its reliable performance and specificity make it an essential component for advancing research in immunology, inflammation, and disease biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08571
Gene ID:
929
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.