The Ox-33 Monoclonal Antibody (AG20004) is a specialized tool for researchers studying rat CD45RA, a protein marker expressed on a subset of rat lymphocytes known for its role in the immune system. This antibody, produced from hybridoma cells, exhibits high specificity and sensitivity towards rat CD45RA and is optimized for various applications including flow cytometry and immunohistochemistry.CD45RA, a surface glycoprotein found on certain immune cells, is associated with distinct functions in immune responses, cell activation, and differentiation. By targeting CD45RA with the Ox-33 antibody, researchers can accurately identify and analyze CD45RA-expressing cells in complex biological samples.
This antibody is particularly valuable for investigations in immunology, transplantation studies, and infectious disease research, providing valuable insights into immune cell subsets and their functions.With its reliable performance and proven efficacy in detecting rat CD45RA, the Ox-33 Monoclonal Antibody (AG20004) offers a powerful tool for advancing scientific understanding of immune cell biology and its implications in various health conditions.
Product Title:
PE Anti-Rat CD45RA Antibody [OX-33]
SKU:
AGEL3424
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
OX-33
Synonyms:
Leukocyte common antigen; high molecular weight form;
Host Species:
Mouse
Reactivity:
Rat
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
24699
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets. CD45RA is one of the CD45 isoforms with a molecular weight of 200-220 kD. It is expressed almost exclusively on B cells. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins, including galectin-1, CD2, CD3, and CD4.