The PE Anti-Rat CD3 Antibody (G4.18) offered by Assay Genie (AGEL2455) is a cutting-edge research tool designed for the detection and analysis of CD3, a vital cell surface protein involved in T cell activation and immune responses. This high-quality antibody, optimized for fluorescent flow cytometry applications, exhibits exceptional specificity and sensitivity in targeting rat CD3 antigens, enabling precise identification and characterization of T cell populations in experimental settings. With its reliable performance and reproducible results, researchers can confidently explore the intricate mechanisms of T cell activation and function in various physiological and pathological contexts.
Whether investigating immune responses, studying autoimmunity, or exploring cancer immunology, the PE Anti-Rat CD3 Antibody (G4.18) provides researchers with a valuable tool to advance their understanding of T cell biology and pave the way for innovative discoveries in immunological research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.