The PE Anti-Mouse/Rat CD29 Antibody (HMβ1-1) available at www.assaygenie.com is a powerful tool for researchers studying cell adhesion and migration in mouse and rat samples. This monoclonal antibody, specifically designed for flow cytometry applications, targets CD29, also known as integrin beta-1, a key cell surface protein involved in cell-extracellular matrix interactions.CD29 plays a crucial role in cell adhesion, migration, and signaling processes, making it essential for understanding cellular behavior in various physiological and pathological contexts. By using the PE Anti-Mouse/Rat CD29 Antibody (HMβ1-1), researchers can accurately detect and analyze CD29 expression on the surface of mouse and rat cells, providing insights into cell adhesion mechanisms and potential therapeutic targets.
With its high specificity and reactivity towards CD29 in mouse and rat samples, this antibody enables precise and reliable flow cytometry analysis, facilitating research in areas such as immunology, cancer biology, and tissue engineering. By targeting CD29, researchers can explore the roles of this integrin in cell adhesion dynamics, migration processes, and disease progression, ultimately advancing our understanding of complex biological systems.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09055 P49134
Gene ID:
16412, 24511
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD protein, also known as integrin β1, VLA-β chain, or GPIIa. It is a member of the integrin family, expressed broadly on leukocytes, endothelial cells, smooth muscle, and epithelial cells. In association with CD49a-f, CD29 forms the VLA-1 through VLA-6 complexes, respectively. It plays an important role in cell-cell or cell-matrix interaction. The HMß1-1 antibody reacts with both mouse and rat CD29. It is able to block cell adhesion and inhibit T cell proliferation.