The PE Anti-Mouse H-2 Antibody (M1/42) is an essential tool for research involving immune responses in mice. This antibody, designed for flow cytometry applications, specifically targets the H-2 protein, a major histocompatibility complex (MHC) molecule in mice. Its high specificity and sensitivity allow for accurate detection and analysis of H-2 expression on various immune cell types, providing valuable insights into immune regulation and function.The H-2 protein plays a crucial role in antigen presentation and immune system function in mice. By targeting this protein, researchers can investigate immune responses, cell interactions, and immune cell differentiation with precision.
This antibody is ideal for immunology studies, vaccine development, and research into autoimmune diseases and infectious agents in mouse models.With its reliable performance and proven efficacy, the PE Anti-Mouse H-2 Antibody (M1/42) from AssayGenie is a valuable resource for researchers exploring the intricacies of the immune system in mouse models. Trust in this antibody to facilitate accurate and insightful investigations that advance our understanding of immune regulation and function.
Product Title:
PE Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2419
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.