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PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2764)

SKU:
AGEL2764
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
RMV-7
Conjugation:
PE
€139 - €319
Frequently bought together:

Description

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PE Anti-Mouse CD51 Antibody [RMV-7]

The RMV-7 Monoclonal Antibody (AGEL2764) is a cutting-edge research tool specifically designed for the study of mouse CD51, a key cell surface protein involved in cell adhesion and migration processes. This antibody, produced from hybridoma cells, exhibits high specificity and sensitivity in recognizing mouse CD51, providing exceptional accuracy in experimental analyses such as flow cytometry and immunofluorescence staining.CD51, also known as integrin alpha V, is a vital component in mediating cell-cell and cell-extracellular matrix interactions, playing a crucial role in various physiological and pathological processes including tissue development, angiogenesis, and cancer metastasis.

By targeting CD51, researchers can gain valuable insights into the mechanisms underlying these biological phenomena, paving the way for innovative discoveries and potential therapeutic interventions.Whether investigating cellular behavior in the context of embryogenesis, wound healing, or tumor progression, the RMV-7 Monoclonal Antibody offers a reliable tool for exploring the intricate functions of CD51 in diverse experimental settings. Its versatility and effectiveness make it an indispensable asset for scientists conducting cutting-edge research in fields such as cell biology, oncology, and regenerative medicine.

Product Title:PE Anti-Mouse CD51 Antibody [RMV-7]
SKU:AGEL2764
Size:25µg, 100µg
Clone No:RMV-7
Synonyms:Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P43406
Gene ID:16410
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

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