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PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2762)

SKU:
AGEL2762
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
RMV-7
Conjugation:
PE
$215 - $491
Frequently bought together:

Description

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PE Anti-Mouse CD51 Antibody [RMV-7]

The Mouse CD51 Monoclonal Antibody (RMV-7) is a specialized research tool offering precise binding to the CD51 protein, essential for studying cell adhesion and migration in various biological systems. This antibody, derived from hybridoma cells, exhibits high specificity towards mouse samples and is ideal for applications such as flow cytometry and immunohistochemistry.CD51, also known as integrin alpha V, plays a crucial role in cell-cell and cell-extracellular matrix interactions, influencing processes like tissue development, wound healing, and tumor metastasis. By targeting CD51 with this monoclonal antibody, researchers can gain valuable insights into the mechanisms governing cellular behavior, particularly in the context of angiogenesis, fibrosis, and cancer progression.

With its ability to selectively recognize and bind to CD51, the RMV-7 antibody opens up avenues for investigating complex cellular pathways and identifying potential therapeutic targets for diseases characterized by dysregulated cell adhesion and migration. Researchers across fields such as oncology, developmental biology, and regenerative medicine can benefit from the specificity and reliability offered by this antibody in their experimental studies.

Product Title:PE Anti-Mouse CD51 Antibody [RMV-7]
SKU:AGEL2762
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RMV-7
Synonyms:Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P43406
Gene ID:16410
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

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