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PE Anti-Mouse CD41 Antibody [MWReg30] (AGEL2305)

SKU:
AGEL2305
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
MWReg30
Conjugation:
PE
€129 - €259
Frequently bought together:

Description

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PE Anti-Mouse CD41 Antibody [MWReg30]

The MWReg30 Monoclonal Antibody (AG10544) is a powerful tool for research involving the CD41 antigen in mouse models. This antibody, derived from hybridoma cells, specifically targets the CD41 antigen found on platelets and megakaryocytes. Validated for use in flow cytometry and immunohistochemistry applications, the MWReg30 antibody enables precise detection and analysis of CD41 expression in various tissues and cell types.CD41, also known as integrin alpha IIb, is a crucial component of platelet function and plays a key role in hemostasis and thrombosis.

By targeting CD41 with the MWReg30 antibody, researchers can explore the dynamics of platelet activation, aggregation, and clot formation, shedding light on processes related to vascular health and cardiovascular diseases. The ability to accurately assess CD41 expression levels in experimental models provides valuable insights for investigations into thrombocytopenia, platelet disorders, and cardiovascular conditions, driving advancements in both basic science and clinical research.

Product Title:PE Anti-Mouse CD41 Antibody [MWReg30]
SKU:AGEL2305
Size:50 Tests, 100 Tests, 200 Tests
Clone No:MWReg30
Synonyms:Itga2b;GPalpha Iib;CD41;GPIIb;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:PE Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QUM0
Gene ID:16399
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

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