The PE Anti-Mouse CD4 Antibody (clone RM4-5) offered by Assay Genie (AGEL3494) is a powerful tool for studying CD4, a crucial cell surface marker primarily found on helper T cells. This antibody, which is conjugated to phycoerythrin (PE), is specifically designed for use in flow cytometry applications.CD4 is a key player in the immune response, aiding in the activation of T cells and orchestrating various immune processes. The RM4-5 antibody is highly specific to mouse CD4 and enables researchers to accurately identify and quantify CD4-expressing cells in mouse samples. Its bright PE fluorescence allows for robust detection and analysis in flow cytometry experiments.
By utilizing the PE Anti-Mouse CD4 Antibody (RM4-5), researchers can delve into various aspects of immune function, including T cell activation, differentiation, and immune response modulation. This reagent is particularly valuable for immunologists, cancer researchers, and those investigating autoimmune disorders, as it provides a precise means of analyzing CD4 expression in experimental systems.Explore the intricate world of mouse CD4 biology with the PE Anti-Mouse CD4 Antibody (RM4-5) from Assay Genie, and unravel new insights into immune regulation and disease pathogenesis.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes and a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a co-receptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase lck.