The PE Anti-Mouse CD4 Antibody (GK1.5) offered by Assay Genie is a crucial tool for researchers studying immune responses and T cell biology in mice. This antibody, specifically designed to target the CD4 cell surface marker, is ideal for flow cytometry applications, enabling accurate identification and analysis of CD4-positive T cells in various experimental settings.CD4, a key marker for helper T cells, plays a central role in coordinating immune responses and regulating immune system functions. The PE Anti-Mouse CD4 Antibody (GK1.5) binds specifically to CD4-expressing cells, providing researchers with a reliable tool for exploring T cell populations in immunology research, infectious disease studies, and autoimmune disorder investigations.
With its high specificity and sensitivity, this antibody allows for precise detection and quantification of CD4 T cells in mouse samples. By targeting CD4, researchers can gain insights into the dynamics of immune cell populations and their interactions, paving the way for advancements in immunotherapy, vaccine development, and understanding of immune-related disorders.Overall, the PE Anti-Mouse CD4 Antibody (GK1.5) from Assay Genie is a valuable resource for researchers seeking to delve deeper into the intricacies of immune responses and T cell biology in mouse models. Its reliability and performance make it an essential tool for a wide range of studies in the field of immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P06332
Gene ID:
12504
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.