The PE Anti-Human CD48 Antibody (156-4H9) available at Assay Genie is a potent tool for research involving the CD48 cell surface protein. CD48 is known for its role in immune regulation and cell signaling, particularly in modulating immune responses. This antibody, specifically designed for use in flow cytometry applications, offers high reactivity with human samples, ensuring accurate and reliable results.By targeting the CD48 protein, this antibody allows for the precise detection and analysis of CD48 expression in various cell types. Researchers in immunology, oncology, and cell biology will find this antibody invaluable for studying the function and dynamics of CD48 in health and disease.
Understanding the intricate mechanisms governed by CD48 is essential for unraveling its implications in immune response modulation and diseases such as cancer, autoimmune disorders, and inflammatory conditions.Enhance your research capabilities with the PE Anti-Human CD48 Antibody (156-4H9) from Assay Genie, a trusted partner in providing high-quality antibodies for cutting-edge scientific investigations.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09326
Gene ID:
962
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.