The PE Anti-Human CD4 Antibody (SK3) offered by Assay Genie is a cutting-edge immunological tool designed for research involving CD4, a vital cell surface protein that plays a key role in the immune system. This antibody, specifically developed for detection and analysis in human samples, is ideal for a wide range of applications in immunology and cancer research.CD4, also known as a T-helper cell marker, is crucial for coordinating immune responses by helping to activate other immune cells. The SK3 antibody, validated for use in flow cytometry and other immunological assays, binds specifically to the CD4 protein, enabling precise and accurate detection in various cell types.
This makes it an invaluable asset for studying immune responses in both health and disease, including infectious diseases, autoimmune disorders, and cancer.By using the PE Anti-Human CD4 Antibody (SK3), researchers can gain deeper insights into the role of CD4 in immune function and its implications in various pathological conditions. This antibody offers high sensitivity and specificity, making it a reliable tool for advancing our understanding of immune regulation and potential therapeutic targets.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.