The Anti-Human CD39 Antibody (A1) offered by Assay Genie is a valuable tool for researchers studying CD39, a key enzyme involved in immunoregulation and immune response modulation. This antibody, designed for use in various immunological assays, is particularly effective in detecting and analyzing CD39 protein levels in human samples.CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1, plays a crucial role in the regulation of immune responses by hydrolyzing extracellular ATP and ADP. This enzymatic activity has implications in various physiological and pathological processes, including inflammation, autoimmune diseases, cancer, and infectious diseases.
The Anti-Human CD39 Antibody (A1) allows for precise and accurate detection of CD39 expression in different cell types, making it an indispensable tool for researchers investigating immune-related mechanisms and developing therapeutic strategies.By targeting CD39, researchers can gain insights into the role of this enzyme in maintaining immune homeostasis and explore its potential as a therapeutic target in diseases characterized by dysregulated immune responses. The Anti-Human CD39 Antibody (A1) provides researchers with a reliable tool to advance their understanding of CD39 function and its implications in immunology and disease pathogenesis.
Product Title:
PE Anti-Human CD39 Antibody [A1]
SKU:
AGEL2289
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
A1
Synonyms:
SPG64;NTPDase1;ATPDase;CD 39;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49961
Gene ID:
953
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details