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PE Anti-Human CD22 Antibody [BU59]

SKU:
AGEL2818
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
BU59
Conjugation:
PE
€169 - €579
Frequently bought together:

Description

PE Anti-Human CD22 Antibody [BU59]

The PE Anti-Human CD22 Antibody (BU59) offered by Assay Genie is a vital tool for researchers studying the CD22 protein, a key B cell receptor involved in immune response regulation. This antibody, specifically designed for use in flow cytometry applications, enables the precise detection and analysis of CD22 expression in human samples.CD22, a member of the immunoglobulin superfamily, plays a crucial role in B cell activation and antibody production. Its function as a regulator of immune signaling pathways makes it a target of interest in studies related to immunology, autoimmune diseases, and B cell malignancies like leukemia and lymphoma.

The PE Anti-Human CD22 Antibody (BU59) provides researchers with a reliable method to identify and analyze CD22-expressing cells, facilitating a deeper understanding of its role in immune function and disease pathogenesis.With its high specificity and sensitivity, this antibody is an essential tool for investigating the complex mechanisms underlying immune responses and developing targeted therapies for various immune-related disorders. Researchers can trust the PE Anti-Human CD22 Antibody (BU59) from Assay Genie to deliver accurate and reproducible results, advancing their investigations into the intricate workings of the immune system.

Product Name:PE Anti-Human CD22 Antibody [BU59]
Product Code:AGEL2818
Clone No:BU59
Synonyms:B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2550)
Conjugation:PE
Form:Liquid
Fluorescent Label:PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Swissprot:P20273
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

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