The Human CD133 Monoclonal Antibody (Clone: W6B3C1) available at AssayGenie is a powerful tool for researchers studying CD133, a key cell surface marker associated with stem cells and cancer stem cells. This antibody, produced through monoclonal antibody technology, exhibits high specificity and sensitivity for human CD133 samples, making it an excellent choice for various applications.CD133, also known as prominin-1, is a glycoprotein involved in various cellular processes, including cell differentiation, proliferation, and tumor initiation. Its presence on the cell surface is often used to isolate and characterize stem cell populations in both normal tissues and tumors. Research into CD133 can provide valuable insights into stem cell biology, cancer progression, and potential therapeutic targets.
The CD133 Monoclonal Antibody (Clone: W6B3C1) recognizes the CD133 protein, allowing researchers to detect and analyze its expression in different cell types and tissues. By utilizing this antibody in experiments such as immunohistochemistry, flow cytometry, and fluorescence microscopy, researchers can further explore the role of CD133 in cancer biology, regenerative medicine, and biomarker discovery.Overall, the CD133 Monoclonal Antibody (Clone: W6B3C1) offers a reliable and specific tool for investigating the functions and implications of CD133 in various research areas. Its versatility and accuracy make it an indispensable asset for studies focused on stem cells, cancer biology, and therapeutic development.
Product Title:
PE Anti-Human CD133 Antibody [W6B3C1]
SKU:
AGEL2730
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
W6B3C1
Synonyms:
Prominin-1;PROM1;AC133;PROML1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
O43490
Gene ID:
8842
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.