PDZK1 Rabbit Polyclonal Antibody (CAB5321)
- SKU:
- CAB5321
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDZK1 Rabbit Polyclonal Antibody |
SKU: | CAB5321 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDZK1 (NP_001188254.1). |
Sequence: | MTST FNPR ECKL SKQE GQNY GFFL RIEK DTEG HLVR VVEK CSPA EKAG LQDG DRVL RING VFVD KEEH MQVV DLVR KSGN SVTL LVLD GDSY EKAV KTRV DLKE LGQS QKEQ GLSD NILS PVMN GGVQ TWTQ PRLC YLVK EGGS YGFS LKTV QGKK GVYM TDIT PQGV AMRA GVLA DDHL IEVN GENV EDAS HEEV VEKV KKSG SRVM FLLV DKET DKRH VEQK IQFK RETA SLKL LPHQ PRIV EMKK GSNG YGFY LRAG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CAP70; CLAMP; PDZD1; NHERF3; NHERF-3; PDZK1 |
Positive Sample: | Mouse kidney,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Membrane, Peripheral membrane protein. |
Calculated MW: | 57kDa |
Observed MW: | 67kDa |
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5174 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |