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PDZK1 Monoclonal Antibody [PAT1A2AT] (CPAB0572)

SKU:
CPAB0572
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1A2AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

PDZK1 Monoclonal Antibody [PAT1A2AT] (CPAB0572)

The PDZK1 Polyclonal Antibody (CPAB0572) is a specialized research tool designed for detecting and analyzing PDZK1 protein levels in various cell types. PDZK1 is a scaffolding protein involved in regulating the function of transporters and receptors in the kidney, liver, and intestine. This antibody, produced in rabbits, offers high reactivity with human samples and has been validated for Western blot applications.PDZK1's role in mediating the localization and activity of key membrane proteins makes it a crucial player in processes like cholesterol metabolism and drug transport. By targeting PDZK1, researchers can gain insights into how these processes are regulated and potentially identify new therapeutic targets for conditions like hyperlipidemia, liver disease, and drug resistance.

The PDZK1 Polyclonal Antibody is a valuable tool for studies in molecular biology, pharmacology, and disease research, providing a means to investigate the complex mechanisms of PDZK1-mediated protein interactions and signaling pathways. Its specificity and sensitivity make it an essential component of any laboratory focused on understanding the molecular underpinnings of cellular function and disease progression.

Product Name:PDZK1 Antibody
Product Sku:CPAB0572
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PDZK1 mAb, clone PAT1A2A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PDZK1 protein 1-519 amino acids  purified from Ecoli.
Clone:PAT1A2AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PDZK1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:PDZK1 is a PDZ domain-containing scaffolding protein which facilitates localization of cell surface proteins and has a key part in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphism in this gene is linked to metabolic syndrome, and overexpression results in drug resistance of multiple myeloma.
Synonyms:PDZ Domain Containing 1, PDZ-Containing Kidney Protein 1, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3, Na/Pi Cotransporter C-Terminal-Associated Protein 1, Sodium-Hydrogen Exchanger Regulatory Factor 3, CFTR-Associated Protein Of 70 KDa, NHERF-3, CAP70, PDZD1, CLAMP, naPi-Cap1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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