The PDZD2 Polyclonal Antibody (PAC01156) is an essential tool for researchers studying PDZD2, a protein involved in regulating cell function and signaling pathways. This antibody, derived from rabbit sources, exhibits high specificity and sensitivity for detecting PDZD2 in human samples, particularly in Western blot applications. By binding to PDZD2, researchers can investigate its role in various cellular processes, making it an invaluable asset in the fields of cell biology and molecular biology.PDZD2 is a key player in cellular processes such as cell signaling, membrane trafficking, and protein interactions. Its intricate functions make it a promising target for research on diseases like neurodevelopmental disorders, cancer, and cardiovascular conditions.
Understanding the mechanisms by which PDZD2 operates is essential for identifying potential therapeutic targets and developing innovative treatment strategies in the future.Overall, the PDZD2 Polyclonal Antibody (PAC01156) serves as a reliable tool for researchers seeking to unravel the complexities of PDZD2 and its impact on cellular function and disease pathology. Its versatility and efficacy make it an indispensable resource in advancing scientific knowledge and discovering new avenues for medical intervention.
PDZD2: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5p13.3Cellular Component: endoplasmic reticulum; cytoplasm; extracellular region; intercellular junction; nucleusBiological Process: cell adhesion
UniProt Protein Details:
NCBI Summary:
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Jul 2008]
