The PDXP Polyclonal Antibody (CAB17455) is a valuable tool for researchers studying the pyridoxal phosphate phosphatase (PDXP) protein, which plays a crucial role in vitamin B6 metabolism. This antibody, generated in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.The PDXP protein is involved in the conversion of pyridoxal phosphate to pyridoxal, a key step in vitamin B6 metabolism. Dysregulation of PDXP has been linked to various diseases, including neurological disorders and cancer.
By detecting and analyzing PDXP expression, researchers can gain insights into the role of this protein in disease pathogenesis and potential therapeutic targets.In summary, the PDXP Polyclonal Antibody is a reliable tool for investigating the function of the PDXP protein in health and disease. Its high reactivity and specificity make it an ideal choice for researchers in the fields of biochemistry, molecular biology, and drug development.
Product Name:
PDXP Rabbit Polyclonal Antibody
SKU:
CAB17455
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PDXP (NP_064711.1).
Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).
Purification Method:
Affinity purification
Gene ID:
57026
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDXP Rabbit pAb (CAB17455) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
