The PDXK Monoclonal Antibody is a highly specific and sensitive tool for research involving the PDXK protein, an important enzyme in the vitamin B6 metabolic pathway. This antibody, produced through monoclonal antibody technology, demonstrates high reactivity with human samples and is validated for use in various applications such as Western blot, immunohistochemistry, and flow cytometry.The PDXK protein is essential for the conversion of vitamin B6 into its biologically active form, pyridoxal phosphate, which plays a critical role in numerous biochemical reactions, including amino acid metabolism and neurotransmitter synthesis.
Dysregulation of the vitamin B6 metabolic pathway has been linked to various diseases, making the PDXK antibody a valuable tool for studying its role in conditions such as cancer, cardiovascular disease, and neurological disorders.By targeting the PDXK protein, researchers can investigate the mechanisms underlying vitamin B6 metabolism and its impact on various physiological processes. This antibody enables precise detection and analysis of PDXK expression in different cell types, providing valuable insights into the biological functions of this enzyme and its potential therapeutic implications.
Product Name:
PDXK Monoclonal Antibody
SKU:
CAB23085
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human PDXK (NP_003672.1).
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
8566
Clone Number:
ARC59845
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PDXK Rabbit mAb (CAB23085) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
