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PDX-1 Monoclonal Antibody (CPAB0733)

SKU:
CPAB0733
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Applications:
WB
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet

PDX-1 Monoclonal Antibody (CPAB0733)

The PDX-1 Polyclonal Antibody (CPAB0733) is a valuable tool for researchers studying PDX-1, a transcription factor involved in the development and function of pancreatic beta cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.PDX-1 is known for its crucial role in regulating the expression of genes involved in insulin production and pancreatic development. Dysregulation of PDX-1 has been implicated in diseases such as diabetes, making it a key target for research in the field of endocrinology.

With the ability to specifically bind to the PDX-1 protein, this antibody enables researchers to detect and analyze PDX-1 expression in different cell types, making it an essential tool for studies focusing on diabetes, pancreas development, and related disorders. By gaining a better understanding of PDX-1 function, researchers can potentially uncover new therapeutic targets for improving the treatment of diabetes and other pancreatic disorders.

Product Name:PDX-1 antibody
Product Sku:CPAB0733
Size:10μl
Host Species:
Immunogen:Recombinant PDX1 E.Coli derived.
Clone:
Reactivity:Other Polyclonal bodies
Applications:Western Blot, Immunohistochemistry
Purification Method:
Isotype:
Background:PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell.
Synonyms:IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1.
Storage Buffer:

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