The PDSS2 Polyclonal Antibody (CAB16557) is a valuable tool for researchers studying the PDSS2 protein, which plays a crucial role in the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain in mitochondria. This antibody, produced in rabbits, is highly specific to human PDSS2 and is validated for use in Western blot and immunohistochemistry applications.PDSS2 has been linked to various health conditions, including mitochondrial disorders and neurological diseases, highlighting its importance in cellular energy production and oxidative stress management.
By targeting PDSS2 with this antibody, researchers can gain insights into the protein's function and potential therapeutic implications in these disease contexts. Overall, the PDSS2 Polyclonal Antibody is a valuable tool for advancing research in mitochondrial biology and related fields.
Product Name:
PDSS2 Rabbit Polyclonal Antibody
SKU:
CAB16557
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-399 of human PDSS2 (NP_065114.3).
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
Purification Method:
Affinity purification
Gene ID:
57107
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-375 cells, using PDSS2 Rabbit pAb (CAB16557) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
