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PDPN P56F7AT Monoclonal Antibody [P56F7AT] (CPAB0653)

SKU:
CPAB0653
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
P56F7AT
Applications:
WB
ELISA
FC
$179
Frequently bought together:

Description

system_update_alt Datasheet

PDPN P56F7AT Monoclonal Antibody [P56F7AT] (CPAB0653)

Based on the information provided in the URL (https://www.assaygenie.com/pdpn-p56f7at-antibody-cpab0653/), it appears that the PDPN Polyclonal Antibody (CPAB0653) is a valuable tool for research involving PDPN, a cell surface glycoprotein associated with cancer progression and metastasis. This antibody is produced in rabbits and is highly specific for detecting PDPN in human samples, making it suitable for use in various research applications, including Western blotting. By binding to the PDPN protein, this antibody enables accurate detection and analysis of PDPN expression in different cell types, making it an essential tool for studies in oncology and cancer biology.

The role of PDPN in promoting cancer cell migration and invasion makes it a promising target for therapeutic intervention in metastatic cancer. Research into the mechanisms of PDPN signaling and its interactions with other molecules is essential for developing targeted therapies that can effectively inhibit cancer progression and improve patient outcomes. Overall, the PDPN Polyclonal Antibody (CPAB0653) is a valuable resource for researchers studying the role of PDPN in cancer biology and exploring potential therapeutic strategies for targeting PDPN-expressing cancer cells.

Product Name:PDPN P56F7AT Antibody
Product Sku:CPAB0653
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PDPN mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDPN amino acids 99-27 purified from Ecoli.
Clone:P56F7AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PDPN antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Podoplanin is a small mucin-like type-1 transmembrane protein, typically expressed in various specialized cell types throughout the body. Podoplanin is a type-I integral membrane glycoprotein with diverse distribution in human tissues. PDPN physiological function is related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. PDPN is expressed in lymphatic progenitor cells and afterwards during mouse development in lymphatic endothelial cells. Podoplanin is a specific marker for lymph vessel endothelial cells. Over-expression of podoplanin significantly elevates endothelial cell adhesion, migration, and tube formation. Inhibition of Podoplanin expression decreases cell adhesion in human dermal lymphatic endothelial cells. Podoplanin is used as a specific marker for lymphatic endothelium in histopathology. Podoplanin expression is increased in nearly all human colon, rectum, and small intestine tumors. AGGRUS may serve as a diagnostic marker that distinguishes seminomas, the majority of which over express the protein, from embryonal carcinoma in testicular germ cell tumors.
Synonyms:Podoplanin, Glycoprotein 36, PA2.26 antigen, T1A, GP36, GP40, Gp38, OTS8, T1A2, HT1A-1, PA2.26, T1-alpha, PDPN.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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