[KO Validated] PDPK1 Rabbit Polyclonal Antibody (CAB1665)
- SKU:
- CAB1665
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] PDPK1 Rabbit Polyclonal Antibody |
SKU: | CAB1665 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 409-556 of human PDK1/PDPK1 (NP_002604.1). |
Sequence: | GSNI EQYI HDLD SNSF ELDL QFSE DEKR LLLE KQAG GNPW HQFV ENNL ILKM GPVD KRKG LFAR RRQL LLTE GPHL YYVD PVNK VLKG EIPW SQEL RPEA KNFK TFFV HTPN RTYY LMDP SGNA HKWC RKIQ EVWR QRYQ SHPD AAVQ |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PDK1; PDPK2; PDPK2P; PRO0461; K1 |
Positive Sample: | HCT116,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein, focal adhesion. |
Calculated MW: | 63kDa |
Observed MW: | 58-68kDa |
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Purification Method: | Affinity purification |
Gene ID: | 5170 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |