The PDPK1 Polyclonal Antibody (CAB1665) is a valuable tool for researchers studying PDPK1, a key signaling molecule involved in various cellular processes, including cell growth, survival, and metabolism. This antibody, produced in rabbits, is highly specific and sensitive for detecting PDPK1 protein in human samples, making it ideal for use in Western blotting applications.PDPK1, also known as 3-phosphoinositide dependent protein kinase-1, is a crucial regulator of the PI3K/Akt signaling pathway, which is known to play a critical role in cell proliferation and survival. Dysregulation of this pathway has been implicated in various diseases, including cancer, diabetes, and cardiovascular disorders.
By targeting PDPK1, researchers can gain insights into the molecular mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies.Overall, the PDPK1 Polyclonal Antibody (CAB1665) provides a valuable tool for investigating the role of PDPK1 in cellular signaling pathways and disease mechanisms. Its high specificity and sensitivity make it an essential reagent for studies in cancer biology, metabolic disorders, and other fields where PDPK1 is known to play a critical role.
Product Name:
[KO Validated] PDPK1 Rabbit Polyclonal Antibody
SKU:
CAB1665
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 409-556 of human PDK1/PDPK1 (NP_002604.1).
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
5170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] PDK1/PDPK1 Rabbit pAb (CAB1665) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
