PDLIM7 Rabbit Polyclonal Antibody (CAB17942)
- SKU:
- CAB17942
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | PDLIM7 Rabbit Polyclonal Antibody |
SKU: | CAB17942 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-190 of human PDLIM7 (NP_998801.1). |
Sequence: | KPQK ASAP AADP PRYT FAPS VSLN KTAR PFGA PPPA DSAP QQNG QPLR PLVP DASK QRLM ENTE DWRP RPGT GQSR SFRI LAHL TGTE FMQD PDEE HLKK S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LMP1; LMP3; PDLIM7 |
Positive Sample: | Jurkat,Mouse lung |
Cellular Localization: | actin cytoskeleton, cytosol, nucleoplasm, Z disc |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9260 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |