The PDLIM7 Rabbit Polyclonal Antibody (CAB17942) is a versatile tool for researchers studying PDLIM7, a protein known to be involved in various cellular processes such as cell signaling and cytoskeletal organization. This antibody, produced by Assay Genie, is highly specific to human samples and is suitable for use in Western blot applications.PDLIM7, also known as Enigma, is a scaffold protein that plays a key role in organizing protein complexes involved in signal transduction pathways. Its functions in cell growth, differentiation, and migration make it a valuable target for research in areas like cancer biology and cell biology.
By using this antibody, researchers can detect and analyze PDLIM7 expression levels in different cell types, providing insights into the protein's role in various biological processes.Overall, the PDLIM7 Rabbit Polyclonal Antibody (CAB17942) is a reliable tool for investigating the functions of PDLIM7 in different cellular contexts, offering valuable information for understanding its involvement in disease pathways and potential therapeutic targets.
Product Name:
PDLIM7 Rabbit Polyclonal Antibody
SKU:
CAB17942
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-190 of human PDLIM7 (NP_998801.1).
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9260
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDLIM7 Rabbit pAb (CAB17942) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
