The PDLIM1 Polyclonal Antibody (CAB6686) is a valuable tool for researchers studying PDLIM1, a protein involved in various cellular processes, including cell signaling and cytoskeletal organization. This antibody, generated in rabbits, specifically detects PDLIM1 in human samples and is validated for use in Western blot applications.PDLIM1, also known as CLP-36, is a PDZ-LIM domain protein that regulates the function of other proteins through interactions with their PDZ-binding motifs. It plays a crucial role in organizing signaling complexes and modulating cellular pathways involved in cell adhesion, migration, and differentiation.
Research into the function of PDLIM1 is important for understanding its role in various diseases, including cancer, cardiovascular disorders, and neurological conditions.By using the PDLIM1 Polyclonal Antibody, researchers can accurately detect and analyze PDLIM1 expression in different cell types, providing insights into its function and potential as a therapeutic target. This antibody is a valuable tool for studies in cell biology, cancer research, and drug development aimed at targeting PDLIM1-mediated pathways.
Product Name:
PDLIM1/CLP36 Rabbit Polyclonal Antibody
SKU:
CAB6686
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human PDLIM1/CLP36 (NP_066272.1).
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17.
Purification Method:
Affinity purification
Gene ID:
9124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDLIM1/CLP36 antibody (CAB6686) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
