The PDK4 Polyclonal Antibody (CAB13337) is a valuable tool for researchers investigating the role of PDK4, a key enzyme involved in metabolic regulation, in various cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.PDK4 is known to play a crucial role in the regulation of glucose and fatty acid metabolism, making it a potential target for research in metabolic disorders such as diabetes and obesity. By targeting the PDK4 protein, researchers can gain insights into the mechanisms underlying metabolic dysfunction and identify potential therapeutic strategies for these conditions.
With its ability to detect and analyze PDK4 expression in different cell types, the PDK4 Polyclonal Antibody is a valuable tool for studies in biochemistry, metabolism, and disease pathology. By understanding the function of PDK4, researchers can ultimately contribute to the development of novel treatments for metabolic disorders and improve patient outcomes.
Product Name:
PDK4 Rabbit Polyclonal Antibody
SKU:
CAB13337
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 102-411 of human PDK4 (NP_002603.1).
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Purification Method:
Affinity purification
Gene ID:
5166
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PDK4 Rabbit pAb (CAB13337) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
