The PDK2 Rabbit Monoclonal Antibody (CAB4737) is a powerful tool for researchers studying PDK2, a key enzyme involved in metabolic regulation and energy production. This antibody, produced using rabbit monoclonal technology, shows high specificity and sensitivity in detecting PDK2 protein in human samples, making it ideal for various research applications, including Western blot analysis.PDK2, also known as pyruvate dehydrogenase kinase 2, plays a vital role in the control of glucose metabolism and energy production in cells. Dysregulation of PDK2 activity has been linked to metabolic disorders, cancer, and other diseases, making it a potential therapeutic target.
By targeting PDK2 with this antibody, researchers can gain valuable insights into its function and explore its potential implications in disease progression and treatment strategies.Overall, the PDK2 Rabbit Monoclonal Antibody (CAB4737) offers a reliable tool for studying PDK2 in a research setting, helping to further our understanding of metabolic regulation and its impact on health and disease.
Product Name:
PDK2 Rabbit Monoclonal Antibody
SKU:
CAB4737
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 308-407 of human PDK2 (Q15119).
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5164
Clone Number:
ARC1113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDK2 Rabbit mAb (CAB4737) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
