PDK2 Rabbit Monoclonal Antibody (CAB4737)
- SKU:
- CAB4737
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PDHK2
- PDKII
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PDK2 Rabbit Monoclonal Antibody |
SKU: | CAB4737 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 308-407 of human PDK2 (Q15119). |
Sequence: | YSTA PTPQ PGTG GTPL AGFG YGLP ISRL YAKY FQGD LQLF SMEG FGTD AVIY LKAL STDS VERL PVYN KSAW RHYQ TIQE AGDW CVPS TEPK NTST YRVS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PDHK2; PDKII; PDK2 |
Positive Sample: | Mouse brain,Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 39kDa/46kDa |
Observed MW: | 46kDa |
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5164 |
Clone Number: | ARC1113 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |