PDK2 Rabbit Polyclonal Antibody (CAB4012)
- SKU:
- CAB4012
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PDK2 Rabbit Polyclonal Antibody |
SKU: | CAB4012 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2). |
Sequence: | PTMA QGVL EYKD TYGD DPVS NQNI QYFL DRFY LSRI SIRM LINQ HTLI FDGS TNPA HPKH IGSI DPNC NVSE VVKD AYDM AKLL CDKY YMAS PDLE IQEI NAAN SKQP IHMV YVPS HLYH MLFE LFKN AMRA TVES HESS LILP PIKV MVAL GEED LSIK MSDR GGGV PLRK IERL FSYM YSTA PTPQ PGTG GTPL AGFG YGLP ISRL YAKY FQGD LQLF SMEG FGTD AVIY LKAL STDS VERL PVYN KSAW RHYQ TIQE AGDW CVPS TEPK NTST YRVS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | PDHK2; PDKII; PDK2 |
Positive Sample: | BxPC-3,Mouse brain,Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5164 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |