PDK1 Rabbit Monoclonal Antibody (CAB8930)
- SKU:
- CAB8930
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PDK1 Rabbit Monoclonal Antibody |
SKU: | CAB8930 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 337-436 of human PDK1/PDHK1 (NP_002601.1). |
Sequence: | STAP RPRV ETSR AVPL AGFG YGLP ISRL YAQY FQGD LKLY SLEG YGTD AVIY IKAL STDS IERL PVYN KAAW KHYN TNHE ADDW CVPS REPK DMTT FRSA |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 IHC-P,1:500 - 1:1000 |
Synonyms: | PDK1; pyruvate dehydrogenase kinase 1; PDK1/PDHK1 |
Positive Sample: | LNCaP,A-549(Low expression control) |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 49kDa |
Observed MW: | 49kDa |
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5163 |
Clone Number: | ARC52376 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |